Evidence engine · Research build 01

Peptide evidence, engineered at scale.

An AI-assisted R&D platform transforming biomedical literature into structured evidence, transparent scoring and research intelligence — from a 126-study MSc prototype to a 94,000+ paper discovery engine.

PubMed retrievalLocal LLM extractionEvidence scoringTranslational-gap analysis
94,826papers in
research universe
Live research snapshot

From prototype to evidence engine.

V1 established that the architecture works. The current programme expands the same logic across a much wider PubMed-derived research universe, with strict triage before expensive deep extraction.

Deep evidence extracted
6,240
current structured snapshot
Tier A completed
6,152
direct-intervention evidence
Scale-run papers
94,826
indexed for discovery
Deep candidates
32,437
strict Tier A + B gate

V1 evidence strength

The prototype deliberately separates the existence of a positive finding from the strength of the underlying evidence.

Strong
22
Moderate
38
Weak
57
Insufficient
9

Study-type mix

The V1 dataset contains enough human and preclinical evidence to expose the translational gap rather than flattening all studies into one category.

126records
Human · 53
Animal/preclinical · 48
Mixed · 17
In vitro · 8
Core research thesis

The signal is not “which peptide works?”

The platform asks a more defensible question: what kind of evidence exists, how strong is it, how confidently was it extracted, and where does preclinical promise fail to translate into robust human evidence? The goal is an inspectable evidence layer that researchers can interrogate — not an automated medical verdict.

Platform layers

Built like an R&D system.

01 · Discover

Programmatic literature retrieval and peptide-hit mapping from biomedical sources, preserving source identifiers and metadata.

02 · Structure

Local LLM extraction converts unstructured abstracts into a defined evidence schema covering study type, design, sample size, outcomes, statistics and safety.

03 · Compare

Deterministic normalisation, evidence scoring and confidence scoring create a comparable analytical layer across heterogeneous research.

Evidence V2 · Full R&D Dataset

The research engine is now an interactive evidence platform.

The current snapshot contains 6,240 structured evidence records across 50 peptide entities, including 3,579 randomised controlled trials and 5,900 human evidence records. Explore study-level results, peptide profiles, translational strength and evidence maturity.

Open Evidence V2 dashboard →